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PSA test > The pros and cons of PSA testing

Your choice

It is up to you whether you have the PSA test to screen for prostate cancer, and whether you continue with annual or biannual checks.   But make sure you base your decision on reliable information, not the latest newspaper, radio or TV article, or some unsubstantiated internet site, and discuss it with your partner.   The Department of Health has recently changed its policy on PSA testing and has agreed that men should be entitled to this test once they have had enough information to make an informed choice.   For more information visit www.cancerscreening.nhs.uk/prostate/.

Pros
  • Allows early detection of potentially curable prostate cancer
  • Permits the doctor to estimate prostate size in a patient with BPH
  • Helps the doctor predict response to certain drugs
  • Allows the doctor to estimate how advanced the cancer is at diagnosis
  • Can be used to monitor men at increased risk of prostate cancer, such as those with a family history
  • Can help the doctor estimate the patient's risk of developing prostate cancer in the future
  • A negative result is reassuring
  • Sequential values provide extra information about cancer risk
  • Helpful for monitoring response to treatment

Cons
  • Clinically insignificant cancers may be detected, causing needless worry and further medical procedures for the patient
  • Men without cancer may have a false-positive result (particularly those with borderline PSA values)
  • A false-negative result may provide unwarranted reassurance
  • There are cost implications – not only regarding the PSA test, but of biopsy and treatment options if the biopsy is positive
  • Those undergoing biopsy are exposed to the risks of bleeding and infection.