| DIRECT EFFECTS OF BISPHOSPHONATES
ON PROSTATE CANCER
Mr Jonathan Coxon St George's Hospital, Tooting |
This project will be looking at effects on prostate cancer cells of bisphosphonates. These are a class of drugs which are known to localize very specifically to bone.
The laboratory-based work will be looking to further investigate findings that bisphosphonates act directly on prostate cancer cells, slowing their adhesion onto bone and their invasion into it, as well as causing cancer cell death.
It is hoped that this would lead to these drugs being used to help prevent growth or slow development of prostate cancer in bone, one of the commonest sites for early spread of the disease.
The project is continued in Project G2003/08 where further reports are available.
Project summary dated 01 September 2003
Project 2002/01