| THE
ROLE OF ADAMALYSIN-THROMBOSPONDINS - A CLASS OF METALLOPROTEINASE
- IN PROSTATE TUMOURGENESIS.
Mr Anthony Riddick Norfolk and Norwich Hospitals |
The funding from Prostate Research Campaign UK has helped research in two ways; firstly it has been used to establish a large bank (as elsewhere a valuable resource) of prostate cancer tissue and, secondly, has sponsored the research titled above.
Proteseases are substances that will break down proteins and are secreted by cancers, enabling the cancer to invade healthy tissue. The bank of prostate tissue has helped the researchers identify a number of protease genes and, therefore, their inhibitors. The latter, potentially have a role in the treatment of prostate cancer. The presence of the actual protease correlates strongly with clinicopathological parameters but there is no clinical work per se in this research.
The establishment of research into prostate disease consequent on the development of the tissue bank will continue at the above establishment.
Research summarised by Prostate Research Campaign UK, 29 July 2002.
Project 1999/09.